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Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason on Signal at JasonMast.05.

Structure Therapeutics said Monday that its daily obesity pill led patients to lose about 16% of their body weight relative to placebo after 44 weeks.

The results of the Phase 2 study could position the company to compete against Eli Lilly and Novo Nordisk in a high-stakes race to develop oral versions of blockbuster GLP-1 injections.

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Lilly reported last year that its experimental GLP-1 pill, orforglipron, led to only about 11% weight loss in a 72-week trial. Orforglipron is expected to win U.S. regulatory approval in the coming weeks, while Novo launched an oral version of its drug Wegovy late last year. 

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