Jim O’Neill (left) is sworn in as HHS deputy secretary by health secretary Robert F. Kennedy Jr. in June 2025. O’Neill, who also served as acting CDC director, was relieved of his job at HHS on Friday.Amy Rossetti/Department of Health and Human Services via AP

Helen Branswell covers issues broadly related to infectious diseases, including outbreaks, preparedness, research, and vaccine development. Follow her on Mastodon and Bluesky. You can reach Helen on Signal at hbranswell.01.

For 28 days last summer, the Centers for Disease Control and Prevention had a director who had been confirmed by the Senate. But in less time than it took Susan Monarez to get approved, she was fired for not kowtowing to her boss, Robert F. Kennedy Jr., over vaccination policy.

It’s starting to look increasingly possible that that less than monthlong stretch may be the only period in the second Trump administration when the agency has a full-time director, according to several public health experts who follow the CDC closely. President Trump hasn’t nominated a new director to replace Monarez, and a White House spokesperson didn’t respond to a request for comment.

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“I think there’s a high likelihood that the CDC will not have a presidentially appointed and a confirmed director in [the remainder of] this administration,” Samuel Bagenstos, a professor of law and social policy at the University of Michigan, told STAT. 

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