Molly Ferguson for STAT

A reader — I’ll call him Jack — recently asked my thoughts on his plans to pursue treatment with lecanemab for his mild cognitive impairment caused by Alzheimer’s disease. So we set up a call to discuss what it is like to live beset by the threat of Alzheimer’s disease, but also the promise of a treatment to slow it.

Jack’s account of his neurologist’s workup and the many steps from diagnosis to anti-amyloid therapy seemed in order. As we explored the details, however, something felt out of order. The problem wasn’t what I was hearing; it was what I wasn’t hearing.

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A very important character was missing.

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